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Literature summary extracted from

  • Sorensen, J.L.; Sleeman, M.C.; Schofield, C.J.
    Synthesis of deuterium labelled L- and D-glutamate semialdehydes and their evaluation as substrates for carboxymethylproline synthase (CarB) - implications for carbapenem biosynthesis (2005), Chem. Commun. (Camb. ), 7, 1155-1157.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.3.1.226 malonyl-CoA + L-glutamate-gamma-semialdehyde Pectobacterium carotovorum
-
 CoA + (2S,5S)-5-carboxymethylproline + CO2
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.226 Pectobacterium carotovorum
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.226 malonyl-CoA + L-glutamate-gamma-semialdehyde
-
 Pectobacterium carotovorum CoA + (2S,5S)-5-carboxymethylproline + CO2
-
 ?
2.3.1.226 malonyl-CoA + L-glutamate-gamma-semialdehyde L-glutamate-gamma-semialdehyde but not D-glutamate-gamma-semialdehyde is a substrate of the enzyme Pectobacterium carotovorum CoA + (2S,5S)-5-carboxymethylproline + CO2
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.3.1.226 CarB
-
 Pectobacterium carotovorum

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.3.1.226 37
-
 assay at Pectobacterium carotovorum

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.3.1.226 7.5
-
 assay at Pectobacterium carotovorum